In 1975, Ronald Pero, Ph.D, chief of cancer prevention research at New York's Preventive
Medicine Institute and professor of medicine in Environmental Health at New York University,
began developing scientific valid ways to estimate individual susceptibility to various chronic
diseases. An individual's immune system responsiveness, or "immune competence," also was
directly linked to certain DNA repairing enzymes, which provided an objective way to assess
disease susceptibility. Pero was also fascinated by the synergistic relationship between various
hormones with other cancer inducing agents to promote disease. If thyroid produces too much of
either thyroxine or thyroid stimulating hormone, cancer risk greatly increases. The nervous
system regulates hormone balances; it too can influence susceptibility to cancer. Along these
lines, various kinds of spinal cord injury are accompanied by a high risk of developing cancer.

Joseph Flesia, D.C., chairman of the board of directors from the Chiropractic Basic Science
Research Foundation, collaborated with Pero in 1986. Measuring 107 individuals who had
received long-term chiropractic care, Pero's team determined that all chiropractic patients were
"genetically normal"; they had no obvious genetic reasons for increased resistance or
susceptibility to disease. Using Pero's test to gauge resistance to hazardous environmental
chemicals, they hypothesized that people with cancer would have a suppressed immune
response to such a toxic burden, while healthy people and people receiving chiropractic care
should have a relatively enhanced response.
The chiropractic patients had 200 percent
greater immune competence than the people that had not received chiropractic,
and 400 percent greater immune competence than people with cancer or other
serious diseases.
Despite a wide range of ages the immune competence did not show a
decline with age.The effects of chiropractic seemed uniform for the entire group.